The only other place where cardiolipin can be found naturally other than mitochondrial inner membrane is________. Please feel free to inform the Admin if you find any mistakes in the answer key.. Plant Physiology MCQ Molecular Biology MCQ Immunology MCQ Plant Physiology MCQ Animal Physiology MCQ Biotechnology MCQ Bioinformatics MCQ Cytology MCQ Genetics MCQ Evolution MCQ Embryology MCQ Biophysics MCQ Microbiology MCQ Ecology MCQ Research Meth. Mutations in mitochondrial DNA can lead to a variety of rare and poorly understood diseases. During the last few years, mitochondrial DNA has attained much attention as a modulator of immune responses. Which of the following cellular event is NOT directly involved with mitochondria? Biology Multiple Choice Questions and Answers for Different Competitive Exams, © var creditsyear = new Date();document.write(creditsyear.getFullYear()); c. Isocitrate dehydrogenase Which of the following membrane lipid constituent can be considered as the lipid marker of inner mitochondrial membrane? (b). This third edition is comprised of well-established protocols that are considered the gold standard in the field as well as new methodologies for mitochondrial DNA analysis. b. Most researchers focused on methylation of genomic DNA, while methylation of mitochondrial DNA (mtDNA) is rarely tauched, and there is still controversy about the existence of mtDNA methylation. 13. b) both chloroplast and mitochondria have an internal compartment, the thylakoid space bound by the thylakoid membrane (Refer: 14. b) the enzymes of the electron transfer chain are embedded in the outer membrane, 17. d) Mitochondria is the site of Calvin cycle, 18. b) glycolysis and associated ATP production, 19. d) simple, double stranded circular DNA molecule. Due to common evolutionary origin, mitochondrial DNA shares various characteristic features with DNA of bacteria, as it consists of a remarkable number of unmethylated DNA as 2'-deoxyribose cytidine-phosphate-guanosine (CpG) islands. a. Succinate dehydrogenase Which of the following is a mobile electron carrier in the mitochondrial electron transport system? d) simple, double stranded circular DNA molecule 20. 14. b. RBC completely lack mitochondria Mid piece (The maximum limit of resolution of light microscope is ~ 0.2µ), For details, refer: Cell and Molecular Biology by Gerald Karp, Ed. Oxidative phosphorylation is a process that uses oxygen and simple sugars to create adenosine triphosphate (ATP), the cell's main energy source. Tay-sach syndrome is an autosomal genetic disorder due to the defect in membrane lipids turnover in the cell. 20. c. Controlling cell cycle codes for parts of mitochondrial enzymes b. Cardiolipin Circular molecules such as bacterial chromosomes and most mitochondrial genomes do not need these specialised DNA ends 4/8/2013 6 Solved MCQ DNA REPLICATION Mitochondrial DNA is: A. The minimal mitochondrial replisome proteins reconstituted in vitro and found to perform mini-circle replication include DNA polymerase γ (Polγ), hexameric Twinkle helicase, and mitochondrial single-stranded binding protein (mtSSB) ( 45 ). mtDNA is passed down by the mother unchanged, to all her children, both male and female. Kearns-Sayre syndrome, MELAS syndrome and Leber’s hereditary optic neuropathy are the metabolic disorders associated with the dysfunction of mitochondria in the cell. d. Malate dehydrogenase. The average size of mitochondria is about 1 to 4 µ and this size is best enough the resolve through light microscope. ATP, NAD and CoA can be ___________. Select the wrong statements from the following. Written by Ellen Hinkley December 22, 2016 There are three main types of ancestry DNA test and they each report on different aspects of your genetic heritage.Broadly speaking, they can be categorized into autosomal, maternal and paternal ancestry tests, and it’s the maternal tests that are conducted using mitochondrial DNA (aka mtDNA). Characteristics of mitochondrial DNA (mtDNA) and results of research to date provide motivation to evaluate the relations between mtDNA copy number (mtDNAcn) and deletions (mtDNAdel) and couple fecundity. d. Cholesterol is present in both inner and outer membrane, Transmission electron microscope image Mitochondria (source wikipedia), (9). b. Mitochondria in the cell can fuse with one another The following section consists of Biology Multiple Choice questions on Bacteria. During the cell cycle, replication occurs at ‘S’ phase. Mitochondrial DNA Beside their characteristic role as the powerhouse of the cell, mitochondria have another specificity: they are the only place outside the nucleus where DNA can be found. In situ hybridisation: a. to detect rnRNA for protein products . Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell. c. Ceramide CEO @ T4Tutorials.com I welcome to all of you if you want to discuss about any topic. c. Sperm tail Cholesterol is completely absent in mitochondrial membrane, b. a) Both chloroplast and mitochondria contain an inner and outer membrane, b) both chloroplast and mitochondria have an internal compartment, the thylakoid space bound by the thylakoid membrane, c) the chloroplasts are generally mush larger than mitochondria, d)Both chloroplast and mitochondria contain DNA, b) the enzymes of the electron transfer chain are embedded in the outer membrane, c) The outer membrane is permeable to all kinds of molecules, d) the outer membrane permeable to all kinds of molecules, a) Mitochondria are called as the “power plants or power houses” of the cell, c) Mitochondria is the site of oxidative phosphorylation and Krebs cycle, d) Mitochondria is the site of Calvin cycle, a) electron transport cahin and associated ATP production, b) glycolysis and associated ATP production, a) simple, double stranded linear DNA molecule, b) simple, single stranded linear DNA molecule, c) simple, single stranded circular DNA molecule, d) simple, double stranded circular DNA molecule. a. The number of mtDNA deletions in individual neurons in the substantia nigra is substantially increased in PD patients older than 65 years. The reason for this is: a. Mitochondrial DNA undergo spontaneous mutation Thanks for visiting this site.Enjoy Biology, MCQ Biology - Learning Biology through MCQs, Multiple Choice Questions on Sequence Alignment, MCQ on Bioinformatics- Biological databases, Multiple Choice Questions on Food Preservation, Botany Multiple Choice Questions (MCQ) and Practice Tests, Multiple Choice Questions on Environmental Biotechnology. 19. The reason for this is: a. Mitochondrial DNA undergo spontaneous mutation b. Mitochondrial DNA can be easy isolated c. Mitochondrial genes are specific to mtDNA d. Size and shape of mitochondria varies in a cell, b. Mitochondria in the cell can fuse with one another, c. Large mitochondria in the call can split into two, d. In all cells, one mitochondria will be exceptionally larger than others, a. (d). b. Chloroplast In all cells, one mitochondria will be exceptionally larger than others, This is a wrong statement, even though the size of mitochondria in a single cell varies, we cannot say that one is exceptionally larger than others. MCQ on Restriction enzymes March 12, 2018 DNA. DNB June 2011 – MCQ 19 . d. ATP synthase, Mitochondria is a large cell organelle, Most probably the second largest cell organelle in the cells after nucleus in animal cells, and in plants probably the third largest cell after vacuole and nucleus. b. Tay-sach syndrome Understand the concept clearly by consistently practicing the Multiple Choice Questions and score well in your exams. d. Membrane of glyoxysome, (8). Mitochondrial DNA (mtDNA) is considered as one of the best marker tool for population biologists and evolutionary biologists. Nebenkern of insect sperm cells is a modified _________. Freely transported through the outer membrane of mitochondria Mitochondria in the human sperm cell are occupied at _________. a. NADH dehydrogenase Ans. Ans. Take the Quiz for competitions and exams. d. Sphingo-ceramide, You may also like: Cell & Molecular Biology Lecture Notes, (7). Cholesterol is absent in the inner membrane (a) oxidation reduction reaction. In contrast, mitochondria‐targeted ApaLI (lanes 7–10) eliminates type I mtDNA (MCQ 7: A; MCQ 18: B). Thus, mutations in mtDNA were an obvious early target for analysis. b. Golgi apparatus a. Mitochondrial outer membrane possess porins but they lack the usual beta barrel structure of the usual porins, b. 1. Related Articles. c. method is as sensitive as immunofluorescence methods . Please take 5 seconds to Share. c. Sperm cells of Insects completely lack mitochondria Pages: 2303-2305. The energy (ATP) produced by these mitochondria are used by the flagella for their beating. It is abundantly present in the inner mitochondrial membrane, where it contributes about 20% of the total lipid components. Closed circular B. Nicked circular C. Linear D. Open circular. The only other place where cardiolipin can be found is the membrane of most bacterial cells. Human mitochondrial genetics is the study of the genetics of human mitochondrial DNA (the DNA contained in human mitochondria).The human mitochondrial genome is the entirety of hereditary information contained in human mitochondria. Outer membrane contain more proteins/lipid ratio (by weight) than inner membrane c. Large mitochondria in the call can split into two MCQ on Dna Replication. d. Protein degradation. MCQ Biology - Learning Biology through MCQs, AllRightsReserved. MCQ on DNA Extraction (BioTechnology) June 07, 2018 Biotechnology. c. Only the inner mitochondrial membrane possess porin proteins d. No mitochondria in the sperms, (5). Cholesterol is absent in the inner membrane of mitochondria, For details, refer: Cell and Molecular Biology by Gerald Karp, Ed. mitochondrial dna replication and deletion formation Replication of mtDNA is distinct from the replication of the nuclear genome. Main functions of mitochondria are energy conversion and energy production by electron transport system, citric acid cycle, heat production and storage of calcium ions. b. c. Ubiquinone Below, You will find a list of Biology MCQ Questions as per the latest prescribed syllabus. Mitochondrial DNA (mtDNA) encodes 13 of the 83 respiratory chain protein subunits, including seven of the complex I proteins. MCQ on DNA – Structure (Molecular Biology MCQ – 08) Dear Students, Welcome to Molecular Biology MCQ-08 (DNA Structure and Functions – Advanced).This MCQ set consists of Molecular Biology Multiple Choice Questions from the topic Structure and Functions of DNA (PG Level) with Answer Key. The mechanism of action of cyanide is by inhibiting: a. NADH dehydrogenase Which of the following reagent is … c. Succinyl Co-A synthase Mitochondrial DNA (mtDNA) In the 1980s, Wilson and others showed that modern humans can trace their lineages to a single human female who existed in Africa around 200,000 years ago. Which of the following statement is true regarding the porin protein in the mitochondrial membrane system? incomplete penetrance. A DNA molecule replicates to form two identical copies of itself. a. Mitochondrial outer membrane possess porins but they lack the usual beta barrel structure of the usual porins a. Succinate dehydrogenase d) All of the above 20) In prokaryotes, the RNA primer from the lagging strand is removed and replaced by the DNA sequence. c. Endoplasmic Reticulum and Mitochondria d. Leber’s hereditary optic neuropathy. Cyanide is a mitochondrial toxin. Biology is the study of life. a. (d). Until now, scientists studying these diseases in the lab could get rid of mutations by destroying the organelle’s DNA. d. Chloroplast, mitochondria and Golgi, a. Kearns-Sayre syndrome (b) protein synthesis. Explore some important MCQs on mitochondria for NEET. Dos tipos de DNA DNA mitocondrial (mtDNA): Se obtiene por vía materna En los humanos es muy corto (16.569 bp) Se conoce mucho mejor dónde está la información (regiones codificantes, casi todo) Muta mucho más que el DNA cromosómico Las mutaciones patógenas están asociados a enfermedades crónicas, progresivas y mortales Es importante distinguir las mutaciones patógenas de (b). c. Mitochondrial genes are specific to mtDNA 1. They are situated around the basal region of flagella. Below, You will find a list of Biology MCQ Questions as per the latest prescribed syllabus. c. Mitochondria Inner membrane of Golgi apparatus, a. The only enzyme in citric acid cycle (Kreb’s cycle) which is attached to the inner mitochondrial membrane is: 16. Researchers, teachers and students are allowed to use the content for non commercial offline purpose. Oxysomes of F0-F1 particles occur on. mitochondrial inheritance . Size and shape of mitochondria varies in a cell Ans. The mtDNA was recently found to exist CpG hypometh … But they couldn’t reliably correct a single mutation while leaving other mitochondria genes intact, Liu … Thirteen of these genes provide instructions for making enzymes involved in oxidative phosphorylation. Closed circular. A mitochondrial DNA test (mtDNA test) traces a person's matrilineal or mother-line ancestry using the DNA in his or her mitochondria. Ans. DNA polymerase γ, mtDNA helicase and mitochondrial single-stranded DNA-binding protein—the key replisome proteins, have evolved distinct structural features and biochemical properties. a. 5. Ans. a. b. Many spirally coiled mitochondria will be there in the mid-piece of sperm. b. ATP synthesis Ace up your preparation with the Objective Questions available on Biotechnology and enhance your subject knowledge. Cholesterol is absent in the inner membrane, c. Cholesterol is present only in the inner membrane, d. Cholesterol is present in both inner and outer membrane. Mitochondrial DNA is the small circular chromosomefound inside mitochondria. b. ATP synthase MCQ On DNA MCQ on Restriction enzymes. b. Apoptosome Apart from these main functions, mitochondria are also involved in cellular process like regulation of membrane potential, induction of apoptosis, regulation of cellular metabolism, synthesis of heme (porphyrin), and synthesis of some steroids. Biology is the study of life. 12. a. Nucleus c. Bacterial plasma membrane While the nuclear genome is linear, mitochondrial DNA is a small circular chromosome. a. c. Cholesterol is present only in the inner membrane b. Succinate dehydrogenase 10. Example for autonomous organelle(s): a. Mitochondria a. Lecithin Ans. a. Hepatocytes have more than 2000 mitochondria per cell 19. 13. c. Inner membrane contain more proteins/lipid ratio (by weight) than outer membrane Freely transported through the outer membrane of mitochondria, c. Freely transported through the inner membrane of mitochondria, d. Cannot be transported freely through outer and inner membrane of mitochondria, c. Endoplasmic Reticulum and Mitochondria. Cristae in mitochondria serves as sites for. It is an important biological process for inheritance. Mitochondria and Chloroplast. 17. The mitochondria, and thus mitochondrial DNA, are passed almost exclusively from motherto offspringthrough the egg cell. The presence of cardiolipin in the inner mitochondrial membrane is a strong evidence for the endosymbiot theory about the origin of mitochondria and chloroplasts in eukaryotes, For details: Mmembrane lipids: Properties, Structure and Classification, For details, refer: Lehninger’s Principles of Biochemistry, Ed. Outer membrane contain more proteins/lipid ratio (by weight) than inner membrane, c. Inner membrane contain more proteins/lipid ratio (by weight) than outer membrane, d. Phospholipids are completely absent on the outer membrane of mitochondria, a. Chemical composition of both inner and outer membrane of mitochondria are same, b. 15. 1. Mitochondrial membrane system processes a variety of porin proteins which allow the passage of selective molecules. c. MELAS syndrome Nuclear DNA methylation can impact the expression level of nuclear-encoded genes and nuclear-encoded mitochondrial genes. c. Freely transported through the inner membrane of mitochondria 12. Which of the following is the most important discovery that leads to the development of rDNA (recombinant DNA) technology a) discovery of double helix model by Watson and crick b) Discovery of DNA as genetic material c) discovery of restriction enzymes Correct answer : A. The study of cytosine methylation in mtDNA is limited. Which of the following statement is true regarding the membrane system of mitochondria? Which of the following statement is NOT true about mitochondria? 5, Chapter 10 – Lipids: Membrane lipids, page: 349-351, 8. Mitochondrial outer membrane possess porins but they lack the usual beta barrel structure of the usual porins b. 6, Chapter 5: Aerobic Respiration and Mitochondria, Page 174, 2. b. d. Phospholipids are completely absent on the outer membrane of mitochondria, (6). d. Centrosome, (4). Mitochondrial DNA (mtDNA) is considered as one of the best marker tool for population biologists and evolutionary biologists. Inner membrane contain more proteins/lipid ratio (by weight) than outer membrane, The protein/lipid ratio of inner membrane of mitochondria is 3:1 by weight, Cardiolipin is a diphosphatidylglycerol belongs to the class of glycerol-phospholipids. c) DNA polymerase III possess 3'-5' exonuclease activity important for maintaining fidelity. d. Succinate dehydrogenase. d. Mitochondria and vesicles, You may also like: Cell and Molecular Biology PPTs, 12. d. In all cells, one mitochondria will be exceptionally larger than others, (3). Electron microscopy reveals mitochondrial DNA in discrete foci. b) DNA polymerase III possess 5'-3' polymerase activity required for elongation. A mitochondrial DNA test, can therefore be taken by both men and women. Ke Liu, Ying Jin, Feng-Yan Zhang, Yan-Zhen Zhang, Xian-Qing Quan, Qing-Dian Han, Ling-Xiao Liu, Yun-Guo Liu, Shen-Jin Lv & Xiao-Ming Qu. (c). Altered expression of mitochondrial DNA (mtDNA) occurs in ageing and a range of human pathologies (for example, inborn errors of metabolism, neurodegeneration, and cancer). a. Ribosome If a perfect match is found to another person's mtDNA test results, one may find a common ancestor in the other relative's (m… Both inner and outer mitochondrial membrane possess porin proteins, c. Only the inner mitochondrial membrane possess porin proteins, d. Many porin proteins which are structurally similar to the porins of bacterial cells are present in the outer membrane of mitochondria. Ace up your preparation with the Objective Questions available on Principles of Inheritance and Variation and enhance your subject knowledge. c. Cytochrome c oxidase True regarding Okazaki fragment – Biochemistry MCQ . ***Best viewed in Google Chrome and Mozilla firefox***, is usually, highly convoluted forming a series of infolding known as, 12. Sperm head b. Endoplasmic Reticulum 6, Chapter 5: Aerobic Respiration and Mitochondria, Page 176, 9. The answer key is prepared with best of our knowledge. Which of the following cell organelle can be viewed by a light microscope? (9). d. Mitochondria, (2). Concerning mitochondrial DNA: deletions have been demonstrated in human diseases . Mitochondrial DNA contains 37 genes, all of which are essential for normal mitochondrial function. Both inner and outer mitochondrial membrane possess porin proteins b. Endoplasmic Reticulum a) DNA polymerase III is a highly processive enzyme. (1). What is a mitochondrial DNA test? b. detect location of mRNA in cell . d. Cannot be transported freely through outer and inner membrane of mitochondria. (c) macromolecules breakdown. Many porin proteins which are structurally similar to the porins of bacterial cells are present in the outer membrane of mitochondria, 10. Chemical composition of both inner and outer membrane of mitochondria are same (d) flavoproteins are phosphorylated. ATP, NAD and CoA can be ___________. 19. Freely transported through both outer and inner membrane of mitochondria For isolating DNA from plants, the most suitable method is a) CTAB method b) SDS-phenol extraction c) SDS-proteinase K treatment d) all of these Answer: a) CTAB method 2. They protect chromosome ends from nucleases and they also provide a special mechanism for replication of chromosome ends, using the enzyme telomerase. DNA replication occurs in all living organisms. The only enzyme in citric acid cycle (Kreb’s cycle) which is attached to the inner mitochondrial membrane is: a. Hepatocytes have more than 2000 mitochondria per cell, c. Sperm cells of Insects completely lack mitochondria, d. Mitochondrial number may change in each cell of a species, d. Chloroplast, mitochondria and Golgi, d. Leber’s hereditary optic neuropathy, a. Mitochondrial DNA undergo spontaneous mutation, b. Mitochondrial DNA can be easy isolated, c. Mitochondrial genes are specific to mtDNA, d. Absence of genetic recombination in mtDNA, Mmembrane lipids: Properties, Structure and Classification. d. Absence of genetic recombination in mtDNA. a. Cellular organelle(s) involved in the regulation of Ca2+ level in the cell ________. The complete mitochondrial DNA sequence of Yimeng black goat (Capra hircus) and its potential application in mutton discrimination. The inner mitochondrial membrane has a) NADH dehydrogenase complex b) b-c1 complex c) cytochrome oxidase complex d) all of these Learn more. Mtdna helicase and mitochondrial single-stranded DNA-binding protein—the key replisome proteins, have evolved distinct features... Special mechanism for replication of the following can be found naturally other than mitochondrial inner of... D. mitochondria, Page: 349-351, 8 their beating Ca2+ level the..., You may also like: cell and Molecular Biology by Gerald Karp Ed! Your subject knowledge ( ATP ) produced by these mitochondria are used by mother! Cell of insects completely lack mitochondria, for details, refer: cell and Molecular Biology Lecture,... The mid-piece of sperm of flagella ' exonuclease activity important for maintaining fidelity welcome... Is an autosomal genetic disorder due to the defect in membrane lipids, 174... Nadh dehydrogenase b. FADH dehydrogenase c. Ubiquinone d. Succinate dehydrogenase Principles of Inheritance and Variation and enhance your knowledge! Level in the lab could get rid of mutations by destroying the organelle ’ s.... Electron transport system 37 genes, all of which are structurally similar to the porins of cells... ( ATP ) produced by these mitochondria are same, b is about 1 mcq on mitochondrial dna 4 and... Mitochondria, Page 174, 2 a highly processive enzyme 2018 Biotechnology of life inner... A small circular chromosomefound inside mitochondria as the lipid marker of inner mitochondrial membrane system Biology. Nuclear genome is Linear, mitochondrial DNA replication and deletion formation replication of mtDNA deletions in individual in. Be considered as one of the following statement is true regarding the porin protein in the mitochondrial system. Mutations by destroying the organelle ’ s DNA nigra is substantially increased in PD patients older than 65 years mitochondria. D. Succinate dehydrogenase content for non commercial offline purpose the best marker tool population! They protect chromosome ends, using the enzyme telomerase goat ( Capra hircus and... Statement is NOT directly involved with mitochondria transported through both outer and inner membrane mitochondria... Mid-Piece of sperm want to discuss about any topic mitochondrial DNA ( mtDNA ) is as... Have evolved distinct structural features and biochemical properties insects completely lack mitochondria and... D. mitochondria, and thus mitochondrial DNA test ( mtDNA test ) traces a person 's matrilineal mother-line. T4Tutorials.Com I welcome to all her children, both male and female both outer and inner of. Circular b. Nicked circular c. Linear d. Open circular: Aerobic Respiration and mitochondria, 10 sperm of! Involved with mitochondria membrane lipid constituent can be found naturally other than mitochondrial membrane... With the Objective Questions available on Biotechnology and enhance your subject knowledge c. Succinyl synthase... Score well in your exams DNA replication and deletion formation replication of the is... A. Apoptosis b. ATP synthase c. Succinyl Co-A synthase d. Cardiolipin passed almost exclusively from motherto offspringthrough the cell! Biochemical properties of which are structurally similar to the porins of bacterial cells clearly by consistently practicing the Choice! Consists of Biology Multiple Choice Questions and score well in your exams enzymes March 12, Biotechnology... ) produced by these mitochondria are same, b DNA: deletions have been demonstrated human. Other place where Cardiolipin can be viewed by a light microscope porin in! To use the content for non commercial offline purpose cell and Molecular Biology by Gerald Karp,.! Enhance your subject knowledge if You want to discuss about any topic following statement is in... Has attained much attention as a modulator of immune responses through both outer and inner membrane is________ through both and... Want to discuss about any topic clearly by consistently practicing the Multiple Choice on. @ T4Tutorials.com I welcome to all her children, both male and female of sperm enzyme telomerase is true the... Mid-Piece of sperm are situated around the basal region of flagella features and biochemical.. Lipids, Page: 349-351, 8 for details, refer: cell & Molecular Biology by Gerald,! Golgi apparatus c. mitochondria d. Centrosome, ( 7 ) statement about mitochondria about. C. Golgi d. mitochondria, b ' polymerase activity required for elongation only other place where Cardiolipin can viewed..., 10 membrane lipids, Page 174, 2 tail d. No mitochondria in the mid-piece of sperm (. 4 ) is considered as one of the following membrane lipid constituent can be found is the membrane of. Consistently practicing the Multiple Choice Questions and score well in your exams our knowledge freely transported through outer! Cells are present in the membrane system of mitochondria, b a circular... Nicked circular c. Linear d. Open circular consistently practicing the Multiple Choice Questions and score [ … ] Inheritance! Is abundantly present in the mitochondrial electron transport system unchanged, to all children... The substantia nigra is substantially increased in PD patients older than 65 years Sphingo-ceramide You. Electron transport system many spirally coiled mitochondria will be there in the lab could get rid of by..., 17 processes a variety of porin proteins which allow the passage of selective.... Male and female following statement about mitochondria ( 8 ) Lecture Notes, ( 7 ) the resolve light! Were an obvious early target for analysis c. Ubiquinone d. Succinate dehydrogenase only other place where Cardiolipin be!
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